Sheldon: "And you're going to have to choke back a hot sob of regret and humiliation as you mumble 'I was, but I chose to go to a party thrown by the one kid from 'Stand by Me' that no one remembers.'"
Bernadette: "Are those Russian rockets safe?"
Howard: "Well, I mean, safe as it can be when it was built by the good folks who brought you Chernobyl."
Sheldon: "Until you either do not go or go to Wil Wheaton's party you are simultaneously my friend and not my friend. I'm characterizing this phenomenon as Schrodinger's Friendship."
Stuart: "Okay if you're going to question the importance of an actor's signature on a plastic helmet from a movie based on a comic book then all of our lives have no meaning!"
Amy: "I don't understand. What different does it make if Leonard goes to Wil Wheaton's party?"
Penny: "Wil Wheaton is Sheldon's mortal enemy."
Amy: "Mortal enemy? Sheldon, I know you're a bit of a left-handed monkey wrench, buy you really have a mortal enemy?
Sheldon: "In fact, I have 61 of them. Would you like to see the list?"
Sheldon: "You've already signed something for me, Brent Spiner, your name on my list. From this momeny on you are my mortal enemy!"
Wil Wheaton: "Don't worry, it doesn't take up a whole lot of your time."